The Human Brain Supercomputer is a top creation of the crime syndicate Neo Zeed. It appears as a boss character in the video game The Revenge of Shinobi and its sequel game, Shinobi III: Return of the Ninja Master. Created as a defense system against potential intruders, The Human Brain Supercomputer utilizes laser devices, firearms, and explosives to destroy Joe Musashi.

The first encounter between Joe Musashi and The Human Brain Supercomputer.


The Revenge of Shinobi

The Human Brain Supercomputer is a top-secret experiment created by Neo Zeed, and is tasked to pilot the organization's air carrier which is housed at a private military base. It was able to detect Joe Musashi after he stowed away onto the air carrier. Unable to move itself, the Supercomputer attacks Musashi with its laser defense system but is destroyed.

Shinobi III: Return of the Ninja Master

The Human Brain Supercomputer was restored when Neo Zeed resurfaced. Now stationed in a high-tech facility to defend Zeed Laboratory and its hideous bioexperiments, it was given an armored pod to move in and was outfitted with various missile and beam weapons, as well as a teleportation system and a reality-distortion field to confuse Musashi's attacks. Despite the advances in its abilities, it was again destroyed by Musashi.